3rd International conference on Brain disorders & Neurodegeneration

"Treatments" can be divided into two categories. 1) Neuroprotective treatments slow, halt, or reverse the underlying neurodegenerative process that causes the loss of cells in the brain. 2) Symptomatic treatments improve the symptoms of Parkinson's disease without slowing the underlying course. All current approved therapies fall into this second category. There is no evidence from randomized, double-blinded, placebo-controlled experiments for a Neuroprotective effect (slowing the underlying disease process in the brain) from any traditional or alternative therapies. For treatment of the symptoms of Parkinson's disease, consider the following evidence: ·        Tai Chi to improve balance and postural stability .  This was a randomized, single-blinded experiment where Tai Chi was compared to traditional resistance training and to stretching. Tai Chi  showed greater improvement in the primary outcomes than the other two...

Noopept is one of the strongest nootropics available on the market today. It provides a boost to overall cognition and has a slight psychostimulatory effect. Contrary to most nootropics, Noopept's effects start within mere minutes of ingestion making it an excellent choice right before mentally demanding tasks. The benefits of Noopept are numerous, to say the least, but the best thing about it is that its effects are cumulative. Noopept has quickly risen in popularity and has made its way into many people’s nootropic stacks due to its impressive effects, ease of its small doses, and its economical price. Whether you are an experienced nootropic user or just getting introduced, Noopept is a worthwhile contender. For all the positive things that Noopept can do for your cognitive health the supplement has only a few occasionally reported minor side effects that should be noted such as headaches, restlessness, dizziness, and irritability. These are most common when Noop...

After binding of the ligand, the receptor tyrosine kinase (RTK) auto phosphorylates Tyrosine -> activates GRB2 -> SOS -> RAS -> downstream kinase -> transcription factors. Think  anabolic / growth factors  - Insulin, IGF-1, FGF, PDGF, EGF Non receptor tyrosine kinase receptors dimerizes -> recruits JAK -> JAK cross-phosphorylate dimer -> activate STAT and dimerize it -> STAT translocates into nucleus and activates transcription. The hormones are mostly related to immunity. Think  acidophils and cytokines . A good mnemonic is PIGG (L) ET: Prolactin, Immunomodulators (cytokine, IL-2, Il-6, IFN), GH, G-CSF, Erythropoietin and Thromobopoietin The key conceptual difference here is RTK has  intrinsic  TK activity and nRTK needs to recruit JAK to have kinase activity. Here is an image that gives you a side-by-side comparison: Reference: Kayee Tong

Is there an association between brain size and Neurodegeneration? There are more variables than brain size involved. If you had a brain MRI performed, and the doctor who interpreted the results rendered your smaller brain like a death sentence, then we have a shared experience. I fled to a specialist - a neuropsychologist - and he stated the same finding was “too vague to have clinical significance.” It would concern me more if I were symptomatic. After months of research, and discussions with every brain specialist under the sun, I stumbled across this insight on my own. My MRI shows I have no “hemosiderin (or iron) deposits” no signs of vascular damage or other anomalies, indicative of a neurodegenerative disease or substance abuse. I drew my own conclusions and shared them with a psychiatrist, and he agreed. I would be more concerned if your MRI showed an accumulation of iron deposits with the global mild atrophy. Though not definitive, together they would...

3rd International conference on Brain disorders & Neurodegeneration April 21 -22, 2020 | Paris, France 3rd International Conference on Brain Disorders & Neurodegeneration is organised by Larix International and scheduled on April 21-22, 2020 in Paris, France.  Neuroscience 2020 aims to collect eminent scientists, analysis students, notable medical specialist, and educationists and professionals to specific their views on the most recent technologies, trends, and considerations in Neuroscience. It focuses on addressing the constant effort being created by soul and students to enhance the present and inventing novel technologies for future. The conference will address the problems being visaged by surgeons and patients and therefore the impact of neurology within the world. Neuroscience 2020 conference provides a platform for organisations, companies, associations, societies, establishments, statutory bodies and alternative authorities and people fascinated by...